Effect of Desflurane v/s Propofol on the Optic Nerve Sheath Diameter (ONSD)

All India Institute of Medical Sciences

Status and phase: Completed; Phase 4

Conditions: Optic Nerve Sheath Diameter; Desflurane; Propofol Target-controlled Infusion

Treatments: Drug: Propofol (Group P); Drug: Desflurane

Study type: Interventional

Funder types: Other

Identifiers

NCT07359508

AllMS (Other Identifier)

2

Details and patient eligibility

About

effect of propofol vs desflurane on ONSD

Enrollment: 146 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient aged 18-60 years ASA grade I or II scheduled for elective laparoscopic cholecystectomy

Exclusion criteria

• patients with ophthalmological and cerebrovascular diseases, systemic infections, psychiatric disorders, pregnancy, Intracranial space occupying lesion, abnormal liver/kidney functions prior myocardial infarction.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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146 participants in 2 patient groups

Propofol group

Experimental group

Description:

propofol infusion will be given in this group after induction of the patient

Treatment:

Drug: Propofol (Group P)

Desflurane

Experimental group

Description:

desflurane inhalation will be given in this group, after induction

Treatment:

Drug: Desflurane