Effect of Desmopressin on the Nocturnal Micturition Frequency in Patients With Parkinson Disease (DEPOPA)

Johannes Gutenberg University (JGU)

Status and phase

Terminated

Phase 4

Conditions

Parkinson Disease

Treatments

Drug: Desmotabs

Study type

Interventional

Funder types

Other

Identifiers

NCT00806468

DEPOPA-2008

Details and patient eligibility

About

This study will be conducted to study the effect of Desmopressin on the nocturnal micturition frequency in patients with idiopathic Parkinson syndrome.

Enrollment

1 patient

Sex

Male

Ages

18 to 85 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Male patients with idiopathic Parkinson Syndrome
18 to 85 years
Nocturnal Pollakisuria > 2 mictions /night (documented in Screening phase )
Na+ i.S > 135 mmol/l
Patient is able to understand all aspects and individual consequences of the clinical trial
An informed consent signed and dated by the patient is available prior to any study specific treatment
The study is consistent with the patients´ request for an appropriate treatment

Exclusion criteria

Intake of the following concomitant medication: Carbamazepin, Oxcarbazepine, diuretics (Furosemide, Torasemide), non steroidal antiphlogistics, Loperamide, antidiuretic hormone analoga (besides study medication), drugs for treatment of bladder disfunction, in particular anticholinergics
Central Diabetes insipidus
Known heart insufficiency (NYHA Stad. III und IV)
clinical relevant kidney insufficiency
Habitual and psychogenic Polydipsia
Hypersensitivity or allergy against the trial medication or any other ingredient of the trial medication
Participation in another clinical trial during or within 6 months prior to this clinical trial
Medical or psychological condition, which might endanger the proper conduction of the clinical trial
Known drug or alcohol abuse