Effect of Dexamethasone on Duration of Lower Extremity Blocks With Bupivacaine in Subjects Having ACL Repair

The University of Chicago

Status and phase: Terminated; Phase 4

Conditions: Duration of Pain Relief

Treatments: Drug: Bupivacaine; Drug: dexamethsone

Study type: Interventional

Funder types: Other

Identifiers

NCT01756560

IRB12-2191

Details and patient eligibility

About

Anterior cruciate ligament reapair is a painful procedure. Single shot femoral and sciatic nerve block only last 12-16 hrs. Since dexamethasone prolongs brachial plexus block, using it in lower extremity blocks will prolong the analgesia to provide better outpatient pain relief after surgery at home.

Enrollment: 2 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age 18-75, no contraindication to regional anesthesia

Exclusion criteria

• peripheral neuropathy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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2 participants in 2 patient groups

control

Active Comparator group

Description:

in this group, plain bupivacaine will be used to block femoral and sciatic nerve

Treatment:

Drug: Bupivacaine

Dexamethasone

Experimental group

Description:

Bupivacaine mixed with dexamethasone will be used to block femoral and sciatic nerve

Treatment:

Drug: Bupivacaine

Drug: dexamethsone