Effect of Dexmedetomidine on QT Interval in Pediatric Patients Under General Anesthesia

Senthil G. Krishna

Status: Completed

Conditions: Surgery

Treatments: Device: ECG

Study type: Observational

Funder types: Other

Identifiers

NCT01917786

IRB13-00171

Details and patient eligibility

About

Various medications used in anesthesia have been implicated in the prolongation of QT interval. Recently, there has been an increase in the use of dexmedetomidine in patients presenting for surgeries given its beneficial sedative, anxiolytic, and analgesic properties. It has several desirable properties including minimal respiratory side effects as well as the ability to decrease intraoperative and postoperative analgesic requirements. In many of the patients who present for routine surgical procedures, dexmedetomidine is a common component of their anesthetic care. This is a study to assess the effects of dexmedetomidine on the QT interval in children presenting for surgery.

Enrollment: 50 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• ASA grade 1 or 2.
• Scheduled to receive dexmedetomidine.

Exclusion criteria

• Known allergy to dexmedetomidine.

Trial design

50 participants in 2 patient groups

Dexmedetomidine patients

Description:

Surgical patients receiving dexmedetomidine.

Treatment:

Device: ECG

Control patients

Description:

Surgical patients not receiving dexmedetomidine.

Treatment:

Device: ECG