Effect of Dexmedetomidine on the Characteristics of High Volume/Low Concentration Ropivacaine in a Caudal Block in Pediatrics

Yonsei University

Status: Completed

Conditions: Ambulatory Orchipexy

Treatments: Drug: Caudal ropivacaine + dexmedetomidine; Drug: Caudal ropivacaine + normal saline

Study type: Interventional

Funder types: Other

Identifiers

NCT02163980

4-2011-0111

Details and patient eligibility

About

The investigators perform this study to evaluate the effects of caudal Dexmedetomidine (DEX) added to high volume/low-concentration of ropivacaine in children undergoing orchiopexy.

Enrollment: 80 patients

Sex: Male

Ages: 1 to 6 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• children undergoing ambulatory orchiopexy,
• ASA status I

Exclusion criteria

• mental retardation,
• developmental delay,
• neurological or psychiatric illness,
• coagulation disorder,
• spinal anomalies

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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80 participants in 2 patient groups, including a placebo group

Caudal ropivacaine + normal saline

Placebo Comparator group

Description:

1.5ml kg-1 ropivacaine 0.15% with normal saline (Control group, n=40).

Treatment:

Drug: Caudal ropivacaine + normal saline

Caudal ropivacaine + dexmedetomidine

Experimental group

Description:

1.5ml kg-1 ropivacaine 0.15% with dexmedetomidine 1 μg kg-1 (DEX group, n=40)

Treatment:

Drug: Caudal ropivacaine + dexmedetomidine