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Effect of Different Concentrations of Lidocaine in Relieving Pain in Wide Awake Hand Surgery Using Tumescence

K

King Edward Medical University

Status and phase

Completed
Phase 1

Conditions

Lidocaine

Treatments

Drug: lidocaine

Study type

Interventional

Funder types

Other

Identifiers

NCT04692896
27/RC/KEMU

Details and patient eligibility

About

Lidocaine has been used along with adrenaline in tumescent anesthesia for a variety of procedures. This has been quite popular especially in wide awake surgery of the hand with no tourniquet. However, the appropriate lidocaine concentration is yet to be established. This randomized control trial will study the minimum effective lidocaine concentration in hand surgery using the tumescent technique.

Enrollment

90 patients

Sex

All

Ages

16 to 60 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  1. Patients aged 16 to 60 years of either gender
  2. Patients with post burn/post traumatic contractures involving fingers & palm
  3. Patients with nerve injury or flexor/extensor tendons injury distal to mid forearm.

Exclusion criteria

  1. Patients with history of ischemic heart disease, chronic liver disease (ALT/AST 40 IU/L), renal disease (creatinine 13mg/dl), bleeding disorder, peripheral arterial disease & peripheral neuro3pathy .
  2. Surgical site infection .
  3. History of allergic hypersensitivity to epinephrine or lidocaine.

Trial design

Primary purpose

Other

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

90 participants in 3 patient groups

0.1% lidocaine
Experimental group
Treatment:
Drug: lidocaine
0.2% lidocaine
Experimental group
Treatment:
Drug: lidocaine
0.3% lidocaine
Experimental group
Treatment:
Drug: lidocaine

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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