Effect of Different Exercises on Quality of Life of Leukemia Patients.

Children's Cancer Hospital Egypt 57357

Status: Completed

Conditions: Quality of Life; Acute Lymphoblastic Leukemia; Exercise

Treatments: Behavioral: Modified strength training; Behavioral: Aerobic exercises

Study type: Interventional

Funder types: Other

Identifiers

NCT03147365

CCHE-ALL003

Details and patient eligibility

About

• To compare between modified strength training program and aerobic exercises on quality of life on children with Acute Lymphoblastic Leukemia.
• To compare between modified strength training program and aerobic exercises on functional capacity on children with Acute Lymphoblastic Leukemia.

Full description

This study will be done to determine any exercise from aerobic exercises or modified strength training program will be more effective on quality of life and functional capacity on children with Acute Lymphoblastic Leukemia .Acute Lymphoblastic Leukemia is wide spread in the world and the children with this disease are fragile so must know the most program effect.

Enrollment: 75 patients

Sex: All

Ages: 8 to 12 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age range from8-12years.
• Children during 3rd phase( maintenance phase of the treatment). According San et al(2007) who found children with Acute Lymphoblastic Leukemia in maintenance phase of treatment can safely perform both aerobic and resistance training .
• Time elapsed since the start of the maintenance phase >20weeks.
• Children with muscle weakness due to chemotherapy.
• The height , weight and body mass index of the child will take on standard scale.
• preserved cardiac structure and function as assisted by echo-cardiogram.
• The children have ability to walk.

Exclusion criteria

Children who have one or more of the following criteria will be excluded from the study:

• Receiving more intensive chemotherapy.
• Mental disabled.
• Sever cardiomyopathy (ejection fraction <40%, ECG will be used as a pretest as it might be a more sensitive tool to exclude angina pectoris).
• Low blood platelet levels (< 50.000 per µl).
• Marked anemia (hemoglobin < 8 g/dl).
• Severe cachexia (i.e., weight mass loss > 35%).
• Pain in bone.
• Inability to walk.
• Sensory disturbance.
• Peripheral neuropathy.

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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75 participants in 3 patient groups

Control group

No Intervention group

Description:

Twenty five children who will not receive any physical therapy treatment.

Study group A

Experimental group

Description:

Twenty five children who will receive physical therapy treatment which include aerobic exercises.

Treatment:

Behavioral: Aerobic exercises

Study group B

Experimental group

Description:

Twenty five children who will receive physical therapy treatment which include modified strength training program.

Treatment:

Behavioral: Modified strength training