Effect of Different Remineralization Gels

Marmara University

Status: Not yet enrolling

Conditions: White Spot Lesion

Treatments: Other: Remineralization gel

Study type: Interventional

Funder types: Other

Identifiers

NCT05868603

müdf.24.04.23

Details and patient eligibility

About

The aim of the study is to treat white spot lesions that occur after orthodontic treatment.

Different gels will be used for remineralization. The study will consist of 45 people between the ages of 15-18. 45 people will be divided into 3 groups.

Full description

Oral hygiene training will be given to each group and a toothpaste containing 1450 ppm fluoride will be given to brush their teeth twice a day.

Essix appliance with reservoir will be made by taking impressions from 30 patients. Remineralization gel will be put into the Essix appliance for 5-7 minutes twice a day for one month.

Enrollment: 45 estimated patients

Sex: All

Ages: 15 to 18 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients aged 15-18 years,
• Presence of white point lesions,
• Volunteering to participate in the research.

Exclusion criteria

• Not having received orthodontic treatment,
• Having a developmental anomaly affecting the enamel,
• Being allergic to milk,
• Having a syndrome affecting the oral cavity.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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45 participants in 3 patient groups

Remineralization gel with CPP- ACP (GC Tooth MousseTM, Tokyo, Japan)

Experimental group

Description:

CPP-ACP containing remineralization gel (Tooth Mousse GC, Tokyo, Japan) will be put into the Essix appliance with a reservoir and applied for 5-7 minutes twice a day for one month. Before and after the applying remineralization gel, the laser fluorescence values will measure with a DIAGNOdent pen (KaVo Dental corporation, East Main street Lake Zurich, lL).

Treatment:

Other: Remineralization gel

Remineralization gel with calcium glycerophosphate (R.O.C.S.® Medical Mineral Gel, Russia)

Experimental group

Description:

Remineralization gel containing calcium glycerophosphate (R.O.C.S.® Medical Minerals Gel, Russia) will be put into the Essix appliance with a reservoir for 5-7 minutes twice a day for one month. Before and after the applying remineralization gel, the laser fluorescence values will measure with a DIAGNOdent pen( KaVo Dental corporation, East Main street Lake Zurich, lL).

Treatment:

Other: Remineralization gel

Control Group

No Intervention group

Description:

No intervention.