Effect of Dilatation and Curettage on the Endometrial Receptivity

Ain Shams University

Status: Completed

Conditions: Embryo Implantation

Treatments: Procedure: D&C; Procedure: ICSI

Study type: Interventional

Funder types: Other

Identifiers

NCT03485235

AS1764

Details and patient eligibility

About

Effect of dilatation and curettage on the endometrial receptivity and pregnancy outcome in patients with recurrent implantation failure

Enrollment: 160 patients

Sex: Female

Ages: 25 to 35 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. All the patients had at least 3 failed trials of IVF-ET with day 5 fresh blastocyst transferred
2. At least 10 high-grade embryos were obtained in the previous trials
3. Level of AMH more than or equal 1.1 ng/ml.
4. Age: Less than or equal to 35 years

Exclusion criteria

1. Patients with uterine pathology e.g. myoma , Asherman syndrome, Septum ,adenomyosis
2. Hydrosalpinx
3. Endometriosis
4. patients with diagnosed autoimmune diseases affecting pregnancy e.g. S.L.E.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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160 participants in 2 patient groups

D&C

Experimental group

Treatment:

Procedure: ICSI

Procedure: D&C

No D&C

Other group

Treatment:

Procedure: ICSI