Effect of Diode Laser on Post-operative Pain After Endodontic Treatment in Teeth With Apical Periodontitis

Biruni University

Status: Completed

Conditions: Postoperative Pain; Apical Periodontitis

Treatments: Procedure: 2.5% NaOCl, %17 EDTA, Distilled water, 30-gauge, side-opening needle (Canal Clean, Biodent, South Korea),; Device: Medency Primo Diode Laser Device (Medency, Vicenza, Italy)

Study type: Interventional

Funder types: Other

Identifiers

NCT04486196

BİRUNİ-BAP-01-01

Details and patient eligibility

About

Aim: This study aims to assess the effect of root canal disinfection with a 980 µm diode laser following chemomechanical root canal preparation on the severity of pain after root canal treatment (RCT).

Materials and Methods: In present study, asymptomatic, single-rooted teeth with periapical index (PAI) score 3 or 4 were included. All patients were treated with two visits of root canal treatment including dressing with calcium hydroxide. Patients were randomly divided into two groups (n: 28). 'Control (no laser)': The final irrigation was performed using 5ml 2.5% NaOCI, followed by 5 ml 17% EDTA and 5 ml distilled water. 'Laser Disinfection (LD)': Root canals were irradiated with 980 µm diode laser after final irrigation at both visits. The pain levels were evaluated using visual analog scale (VAS) after 8, 24, 48 hours and 7 days. In addition, analgesic intake and time intervals were recorded by patients. The collected data were statistically analyzed with the Chi-square and Mann-Whitney U test (p<0.05).

Enrollment: 60 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy patients
• Patients that had asymptomatic, single-rooted teeth with PAI score 3 or 4

Exclusion criteria

• antibiotic use with in the last month,
• anti-inflammatory analgesic use within the last five days,
• systemic disorder, pregnancy or lactation,
• traumatic occlusion,
• presence of other teeth requiring RCT,
• teeth with root canal fillings,
• calcified canals,
• root resorption,
• periodontal diseases,
• sinus tracts
• severe crown destruction preventing rubber-dam application

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 2 patient groups

Control (No Laser) Group

Experimental group

Description:

The final irrigation was performed using 5ml 2.5% NaOCI, followed by 5 ml 17% EDTA for 3 min and 5 ml distilled water.

Treatment:

Procedure: 2.5% NaOCl, %17 EDTA, Distilled water, 30-gauge, side-opening needle (Canal Clean, Biodent, South Korea),

Laser Disinfection (LD) Group

Experimental group

Description:

After final irrigation was performed using 5ml 2.5% NaOCI, followed by 5 ml 17% EDTA for 3 min and 5 ml distilled water, root canals were irradiated with 980 nm diode laser coupled with optical fiber 200 µm with setting at the average power 1.2-W in pulsed mode. 10 seconds irradiation followed by 10 seconds pause, which comprised one lasting cycle. This cycle was applied 4 times for each root canal. The optical fiber (Medency) was inserted 1 mm short of the apex and the root canals were slowly (at a speed of 2mm/s) irradiated from apical to coronal in continuous circling movements to treat all dentinal tubules in one cycle for each power.

Treatment:

Device: Medency Primo Diode Laser Device (Medency, Vicenza, Italy)