Effect of Drinking Carbohydrate-containing Fluids on Gastric Residual Volume in Elderly Patients

Seoul National University

Status: Completed

Conditions: Fasting

Treatments: Other: Carbohydrate fluid; Other: Non-carbohydrate fluid

Study type: Observational

Funder types: Other

Identifiers

NCT04514380

B-2008/633-301

Details and patient eligibility

About

In the past, some guidelines advised no oral intake for at least 8 hours before any surgery. However, research has shown risks associated with excessive fasting, such as postoperative insulin resistance, and advantages in shorter fasting protocols, such as reduced postoperative nausea and vomiting.

The perioperative fasting guidelines of the European Society of Anaesthesiology focus on preoperative carbohydrates. They hold that it is safe for patients to drink carbohydrate-rich fluids up to 2 hours before elective surgery and that drinking carbohydrate-rich fluids improves subjective well-being, reduces thirst and hunger, and reduces postoperative insulin resistance at an evidence level of 1++. Nevertheless, data on drinking carbohydrate fluids before surgery in elderly patients are limited.

In our institution, there are two clinical pathways for total knee arthroplasty according to the surgeons. One difference is whether carbohydrate fluids drink or not before surgery. The purpose of this study, therefore, is to assess gastric volume in fasted elderly patients using ultrasound after they drank carbohydrate fluids 2 hours before surgery and to compare with matched patients using age, body mass index, and comorbidity, who did not drink carbohydrate fluids before surgery.

Enrollment: 64 patients

Sex: All

Ages: 65 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients undergoing total knee arthroplasty
• Age: 65~85 yeas
• ASA 1~3

Exclusion criteria

• Age < 65 years
• ASA >= 4
• Diabetes mellitus
• Chronic kidney disease

Trial design

64 participants in 2 patient groups

Group C

Description:

Patients drank carbohydrate fluid 2 hours prior to surgery according to the routine fasting protocol by surgeon A.

Treatment:

Other: Carbohydrate fluid

Group N

Description:

Patients did not drink carbohydrate fluid 2 hours prior to surgery according to the routine fasting protocol by surgeon B.

Treatment:

Other: Non-carbohydrate fluid