Effect of Duration and Follicle Diameter During Oocyte Pick up on Embryological Parameters

Eurofertil IVF Health Center

Status: Completed

Conditions: Embryologic Parameters; Duration; Follicle Size

Treatments: Procedure: follicle diameter and duration of procedure

Study type: Observational

Funder types: Other

Identifiers

NCT05666401

Eurofertil-OPU

Details and patient eligibility

About

Investigators aim to investigate if the time spent for smaller follicles worth to deal with. The difference between follicle groups are recorded for embryological parameters. Results will be analysed for yielding transfer embryo and pregnancy rates between groups.

Full description

There are papers about follicle dimensions and volumes studying their effect on embryologic parameters. But most of these studies are far from practical approach and are not easily applicable, such as 3D volumetric measurement is not feasible for most of the clinics. Also one of the points important for us it to evaluate the duration of the procedure and the possible positive effect of shortening the duration for better results. Investigators plan to measure the follicles just before puncture and arrange two groups. Group 1,follicles with diameter of 17 mm and more, and group 2 follicles between14-17 mm. Maturation, fertilization, cleavage characteristics are recorded. The source of chosen transfer embryo and crio-preserved embryos per cycle is also point of interest.

Enrollment: 291 patients

Sex: Female

Ages: 20 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 20-40 year old women

Exclusion criteria

• History of recurrent implantation failure (RIF)
• Known chromosomal abnormality
• Severe male factor and azospermia

Trial design

291 participants in 2 patient groups

group 1

Description:

follicles with a diameter of 17 mm and more

Treatment:

Procedure: follicle diameter and duration of procedure

group 2

Description:

follicles with a diameter of 14 mm to 17 mm

Treatment:

Procedure: follicle diameter and duration of procedure