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Effect of Early Enteral Nutrition on Serum Acetylcholine Level and Inflammation in Critically Ill Patients

N

Nanjing PLA General Hospital

Status

Completed

Conditions

Inflammation
Enteral Nutrition
Critical Illness

Study type

Observational

Funder types

Other

Identifiers

NCT03612206
2016NLYZDRC022

Details and patient eligibility

About

Early enteral nutrition(EEN) is an important treatment for critical ill patients and attenuate systemic inflammation, but the mechanisms are not clear. Thus the investigator conducted this study to observe if EEN affects systemic inflammation though regulation of blood acetylcholine

Enrollment

113 patients

Sex

All

Ages

18 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • initiating enteral nutrition within the first 24-48h after intensive care unit (ICU) admission
  • age more than 18 years
  • Acute Physiology and Chronic Health Evaluation II (APACHE II) score >8

Exclusion criteria

  • not expected to survive 24 hours
  • pregnancy
  • any terminal stage disease

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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