Effect of Early Lifestyle Intervention on Perinatal Outcomes in High-risk Women for Gestational Hyperglycemia

Tianjin Central Hospital of Gynecology Obstetrics

Status

Not yet enrolling

Conditions

GDM

Treatments

Behavioral: Individual lifestyle management

Study type

Interventional

Funder types

Other

Identifiers

NCT07141173

2025KY107

Details and patient eligibility

About

This study aims to explore whether early intervention for high-risk groups of gestational hyperglycemia can improve insulin resistance and effectively prevent the occurrence of GDM, and evaluate which pathophysiological subtypes of GDM have the best effect on improving maternal and fetal adverse prognosis, so as to provide evidence for stratified management and individualized clinical intervention of high glucose groups in pregnancy

Enrollment

604 estimated patients

Sex

Female

Ages

18 to 45 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

18-55 years old
6-14 weeks of pregnancy
at least one risk factor for GDM
signed a written informed consent

Exclusion criteria

Individuals diagnosed with diabetes or prediabetes prior to pregnancy
currently taking medications affecting blood glucose levels such as metformin
women at risk of miscarriage
individuals with chronic conditions (such as uncontrolled hypertension, severe heart disease)
those with movement disorders or contraindicated conditions for physical activity
patients undergoing gastrointestinal surgeries that alter glucose absorption
those unable to maintain regular prenatal care (such as non-compliance with medical instructions or mental health issues).