Effect of Early Mobilization Exercises After Coronary Artery Bypass Graft

Cairo University (CU)

Status: Completed

Conditions: Coronary Artery Bypass Graft CABG

Treatments: Other: usual care using mobilization and breathing exercise; Other: aerobic exercise using cycle ergometer in addition to usual care; Other: resisted exercise using weights and dumbbells in addition to usual care

Study type: Interventional

Funder types: Other

Identifiers

NCT06801314

P.T.REC/012/005234

Details and patient eligibility

About

purpose: This study aims to assess the effects of early mobilization exercises guided by wearable technology on functional capacity after coronary artery bypass graft Methods: Patients will be randomly assigned into three groups: Group A will receive usual care, Group B will receive usual care in addition to aerobic exercise, and Group C will receive usual care in addition to resistance exercise. both the aerobic exercise group and the resistance exercise group will be guided by wearable artificial intelligence ECG monitors for real-time support and guidance, and they will stop exercise when any adverse events occur.

Exercises will be started early from post operative CABG until patients discharge and measurements will be taken at baseline and before discharge

Full description

A) Procedure for evaluation and training

Equipment:

The following instruments will be used:

• Pulse oximeter: It will be used for measuring oxygen saturation and Heart rate before, during, and after sessions and during exercise test
• Intelligent cardiac monitor: used during 6MWT to detect any adverse events during and immediately after the test and also be used during sessions
• Rating of perceived exertion: to estimate effort and exertion during the test and working phase.
• Cycle ergometer: upper and lower pedaling machine will be adjusted to suit all patients' height during exercise sessions
• Dumbbells and weights will be used during exercise sessions Exercise (treatment) procedures
• Group (A): (usual care group):

Start early mobilization exercises and deep breathing exercises with wound support daily

• Group (B): (aerobic exercise group): Patients in this group will receive usual care and cycle ergometer aerobic exercise Mood of exercise: continuous aerobic exercise
• Modality of exercise: cycle ergometer with upper and lower pedaling at the same time with adducted shoulders.
• Intensity of exercise: low to moderate intensity and HR (calculated as recommended by the American College of Sports Medicine (ACSM) and tolerated up to 20-30 bpm above the resting HR), BP, SpO2 and low to moderate rate of perceived exertion through the Borg Scale (10-13) will be monitored during cycling
• Duration: 15-20 min, including 5 min warm-up, 5 min cool down and a working phase from 5-10 min
• Frequency: Daily until discharge
• Group (C): (resisted exercise group):

Patients in this group will receive usual care and resisted exercise

• Mode: Resisted exercise
• Modality: dumbbells or sandbags tied around main groups of muscles Resistance exercises consisted of muscle training with dumbbells for the upper limb (UL) (biceps, triceps, and shoulder flexors) and sandbags for the lower limb (LL) (quadriceps, hamstrings, abductors, and calves).

Intensity of exercise: the load that the patient can lift for 10-12 repetitions at RPE of 10-13 and 1-2 sets Both the aerobic exercise group and the resistance exercise group will be guided by wearable artificial intelligence ECG monitors to provide real-time support and guidance and stop exercise when adverse events occur.

Enrollment: 84 patients

Sex: All

Ages: 45 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

1-post -operative clinically stable patients with hemodynamic stability through measurement of respiratory rate( >8<30) breaths/min , Heart rate (>40<130) beats /min , Spo2>90% 2-both lower limbs will be physically functional 3-CABG surgery 4-Their age will be ranged from 45-65 years old

- Exclusion Criteria:

1. Respiratory insufficiency after surgery manifesting hypoxemia with partial pressure of oxygen in arterial blood <60 mmHg
2. Cardiogenic shock
3. acute renal failure
4. contra-indicated to submaximal exercise test
5. cardiac arrhythmia
6. locomotor/neurological limitation to ambulation
7. physiological compensatory tachycardia in case of (anemia, high tempreture and infection)
8. high blood pressure at rest (systolic blood pressure >160mmHg or diastolic blood pressure >100 mmHg -

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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84 participants in 3 patient groups

control group (A) usual care

Active Comparator group

Description:

patients in this group will receive usual care including moibilizations and breathing exercise

study group (B)aerobic exercise (using cycle ergometer) in addition to usual care

Experimental group

Description:

Patients in this group will be received usual care and cycle ergometer aerobic exercise

Treatment:

Other: aerobic exercise using cycle ergometer in addition to usual care

study group(C)resisted exercise group (using weights and dumbbells) in addition to usual care

Experimental group

Description:

Patients in this group will be received usual care and resisted exercise

Treatment:

Other: resisted exercise using weights and dumbbells in addition to usual care