Effect of Early Pain Management at Triage on Opioid Consumption

University of Monastir

Status: Completed

Conditions: Acute Pain

Treatments: Drug: Tramadol/Paracetamol combination; Drug: Paracetamol; Drug: Placebo Oral Tablet

Study type: Interventional

Funder types: Other

Identifiers

NCT03243006

Triage treatment

Details and patient eligibility

About

introduction: Pain remains one of the most common reasons of emergency department admission. Opioids are overprescribed in emergency departments to treat severe pain.

objective: assessing the impact of ealy pain pain management on the use of intravenous morphine and on patient satisfaction.

Enrollment: 1,500 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• over 18 years of age
• a visual analog scale (VAS) equal to or higher than 30/100 ,
• having given consent to participation
• No contraindications to products used in the course of the study.

Exclusion criteria

• having a vital distress that does not allow an adequate assessment of the intensity of the pain
• an inability to assess pain intensity according to the VAS,
• swallowing disorders or inability , or a contraindication or an allergy to the treatments used.

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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1,500 participants in 3 patient groups, including a placebo group

group Placebo

Placebo Comparator group

Description:

Patients in this group (Placebo Oral Tablet) received two placebo tablets

Treatment:

Drug: Placebo Oral Tablet

group Paracetamol

Active Comparator group

Description:

Patients in this group received two 500 mg paracetamol tablets

Treatment:

Drug: Paracetamol

group Tramadol/Paracetamol combination

Active Comparator group

Description:

Patients in this group (Tramadol/Paracetamol combination ) received 2 tablets of Tramadol/Paracetamol combination (37.5mg/325mg)

Treatment:

Drug: Tramadol/Paracetamol combination