Effect of EDDY Sonic Irrigation on Root Canal Microbiota and Pain in Asymptomatic Apical Periodontitis

Abdulkadir Tiftik,DDS

Status: Completed

Conditions: Dental Pain; Root Canal Infection; Asymptomatic Apical Periodontitis; Periapical Diseases

Treatments: Device: EDDY Sonic Activation; Procedure: Conventional Syringe Irrigation

Study type: Interventional

Funder types: Other

Identifiers

NCT07120126

20/5

Details and patient eligibility

About

This randomized controlled clinical trial aimed to evaluate the effect of sonic activation using the EDDY device on root canal microbiota and postoperative pain in teeth with asymptomatic apical periodontitis. Forty patients were assigned to either a sonic activation group (EDDY) or a conventional irrigation group. Bacterial samples were collected before and after root canal treatment and analyzed using real-time PCR. Postoperative pain was assessed using a Numerical Rating Scale at various time intervals. The results showed that EDDY sonic activation significantly reduced bacterial load, while no statistically significant difference was found in postoperative pain between the groups.

Full description

This prospective, randomized controlled clinical trial was conducted to assess the impact of sonic irrigation using the EDDY device on the reduction of intracanal microbiota and on postoperative pain following root canal treatment of teeth with asymptomatic apical periodontitis. Forty participants with single-rooted teeth were randomly allocated into two groups: the EDDY group, which received final irrigation activated with the EDDY sonic system, and the control group, which received conventional syringe irrigation. Microbiological samples were collected before and after instrumentation and were analyzed using real-time PCR to detect specific bacterial taxa. Postoperative pain levels were recorded using the Numerical Rating Scale at multiple time intervals up to 48 hours after treatment. The results demonstrated a statistically significant reduction in bacterial load in the EDDY group compared to the control group, but no significant difference in postoperative pain was observed. The findings support the use of EDDY sonic activation as an effective method for enhancing root canal disinfection.

Enrollment: 40 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Aged 18-65 years
• Presence of a single-rooted tooth diagnosed with asymptomatic apical periodontitis
• No previous endodontic treatment on the involved tooth
• Good general health (ASA I or II)
• Ability to provide informed consent

Exclusion criteria

• Teeth with internal or external resorption
• Pregnant or breastfeeding women
• Systemic antibiotic or anti-inflammatory drug use within the past 30 days
• Patients with periodontal pockets >4 mm on the affected tooth
• Known allergy to sodium hypochlorite or EDTA
• Patients who failed to attend postoperative pain follow-up

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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40 participants in 2 patient groups

EDDY Group

Experimental group

Description:

Patients in this group received final irrigation using the EDDY sonic activation device after standard root canal instrumentation.

Treatment:

Device: EDDY Sonic Activation

Conventional Irrigation Group

Active Comparator group

Description:

Patients in this group received final irrigation with conventional syringe irrigation after standard root canal instrumentation.

Treatment:

Procedure: Conventional Syringe Irrigation