Effect of EECP on Anterior Ischemic Optic Neuropathy (AION)

Sun Yat-sen University

Status: Unknown

Conditions: Anterior Ischemic Optic Neuropathy

Treatments: Drug: Aspirin; Device: Enhanced external counterpulsation

Study type: Interventional

Funder types: Other

Identifiers

NCT01768260

Eye EECP-1

Details and patient eligibility

About

Enhanced External Counterpulsation(EECP) therapy may promote the recovery of visual function by improving the blood perfusion of eyes. The present study aims to investigate the effect of EECP on Anterior Ischemic Optic Neuropathy.

Full description

Patients with Anterior Ischemic Optic Neuropathy are randomized into two groups: one group receive standard medical treatment for ischemic optic neuropathy, the other group plus EECP therapy besides standard medical treatment.

Enrollment: 40 estimated patients

Sex: All

Ages: 40 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• ischemic optic neuropathy
• within 1 month

Exclusion criteria

• Hemorrhagic disease
• thrombophlebitis or infection lesions
• severe hypertensive patients
• Atrial fibrillation
• Aortic regurgitation

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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40 participants in 2 patient groups

Enhanced External conterpulsation

Active Comparator group

Description:

Enhanced external counterpulsation (EECP) is a noninvasive modality for the treatment of ischemic cardiovascular disease. EECP therapy is done by sequential inflation of 3 sets of cuffs wrapped around the lower extremities during diastole and deflation of the cuffs during systole.

Treatment:

Device: Enhanced external counterpulsation

Drug: Aspirin

aspirin

Active Comparator group

Description:

The subjects with Anterior ischemic Optic Neuropathy received aspirin therapy.

Treatment:

Drug: Aspirin