Effect of Electrosurgery on Blood Loss and Intraoperative Transfusions in Musculoskeletal Tumor Surgery

University Hospital Muenster

Status: Unknown

Conditions: Electrosurgery; Transfusion Rate; Blood Loss, Surgical; Tumororthopaedics

Treatments: Device: Application of novel electrodes

Study type: Observational

Funder types: Other

Identifiers

NCT05164809

202101

Details and patient eligibility

About

Resection of malign musculoskeletal tumors and reconstruction with large tumor prostheses often results in relevant blood loss requiring hemodynamic stabilization and transfusion.

The use of novel electrosurgical electrodes is assessed retrospectively regarding the potential to reduce blood loss and the need for transfusions.

Full description

Background Resection of malign musculoskeletal tumors and reconstruction with large tumor prostheses often result in relevant blood loss requiring hemodynamic stabilization and transfusion. Since machine autotransfusion is contraindicated in tumor surgery, other measures are necessary to reduce intraoperative blood loss.

Objectives Tungsten needle electrodes can be used to simultaneously cut skin and seal bleeding vessels for superficial dissection. Spatula electrodes coated with Teflon (polytetrafluoroethylene PTFE) are used for coagulation and dissection of deeper tissues. The coating reduces eschar build-up and thus smoke creation compared to conventional stainless-steel electrodes. This study assesses the effect of these novel electrodes on blood loss and transfusion rates.

Methods:

The investigators retrospectively investigate all cases of tumor resection and reconstruction with tumor prostheses that were operated five years before the introduction of the new electrodes (2012-2016) and five years after (2018-2021) by one single surgeon with over 25 years of experience. Data are extracted from digital patient records and analyzed by descriptive statistics and t-test for normally distributed data or Mann-Whitney test in case of non-normal distribution.

Enrollment: 150 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients who received hemipelvectomy, hip disarticulation, or major tumor prosthesis implantation at our hospital between 2010 and 2021
• Operated by one single surgeon

Exclusion criteria

• Implantation of a Megaprosthesis without history of tumor

Trial design

150 participants in 2 patient groups

Tungsten/Teflon +

Description:

Dissection with novel electrodes (Tungsten needle electrode + Teflon coated Spatula electrode)

Treatment:

Device: Application of novel electrodes

Tungsten/Teflon -

Description:

Dissection without novel electrodes (Scalpel + Steel Spatula Electrode)