Effect of Elliptical Training on Metabolic Homeostasis in Metabolic Syndrome

Cairo University (CU)

Status: Unknown

Conditions: Metabolic Syndrome

Treatments: Behavioral: exercise training on elliptical device; Behavioral: group B (control group)

Study type: Interventional

Funder types: Other

Identifiers

NCT04635202

P.T.REC/012/002896

Details and patient eligibility

About

The growing prevalence of metabolic syndrome (MetS) in the worldwide is becoming a serious health problem and economic burden. MetS has become a crucial risk factor for the development of type 2 diabetes mellitus (T2DM) and cardiovascular diseases (CVD). The rising rates of CVD and diabetes, which are the two leading causes of death. To prevent the progression of MetS to diabetes and CVD, regular physical activity is required.

Elliptical trainer device is a relatively new modality of exercise and is advertised to be superior to a treadmill because of the low joint impact and the more reasonable costs of an elliptical trainer compared to a treadmill. Additional quantitative research is needed to further evaluate the effectiveness of elliptical trainers and the physiological and perceptual responses to the machine.

Full description

Forty sedentary MeTS patients (from both sexes) will be randomly divided to group A and group B.

-Group A (Elliptical training group): This group (n=20) will receive aerobic training on an elliptical trainer for 16 weeks (3 sessions per week). The session will start with 5 minutes warming up at 50 % of maximal heart rate (MHR), 20-minute continuous ET at 70% of MHR, 12 minutes (4×3) intervals at 90% of MHR with a 3-minute active recovery at 70% of MHR between intervals, and finally 5-minute cool-down period at 50% of MHR.

Group B: this group will continue their normal daily physical activities without any additional training

Enrollment: 60 estimated patients

Sex: All

Ages: 30 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• The MeTS subjects who will have three or more of the following criteria: 1) waist circumference more than 102 cm, triglycerides more than 150 mg/dL, 3) blood pressure (BP) more than 130/85 mmHg, 4) high-density lipoprotein (HDL) less than 40 mg/dL, .

Exclusion criteria

• Renal, pulmonary, cardiac, vascular, respiratory, hepatic, autoimmune disorders.
• Smoker, addictive, cancer, and alcoholic patients.
• Lower limb arthritis or any orthopaedic problem will hinder the training.
• Participation in any type of sport training in the previous 6 months.
• Pregnant or lactating women.
• Patients with thyroid gland dysfunction.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

---

60 participants in 2 patient groups

group A

Experimental group

Description:

patients (n=30) in this group will receive 16 weeks of elliptical training on elliptical trainer, 3 times per week. the training will start with 5 minutes warming up at 50 % of maximal heart rate (MHR), 20-minute continuous ET at 70% of MHR, 12 minutes (4×3) intervals at 90% of MHR with a 3-minute active recovery at 70% of MHR between intervals, and finally 5-minute cool-down period at 50% of MHR

Treatment:

Behavioral: exercise training on elliptical device

Group B (control group)

Other group

Description:

patients (n=30) in this group will receive general advises on maintaining physical activities

Treatment:

Behavioral: group B (control group)