Effect of Endovascular Inferior Mesenteric Artery Embolization on Colonic Perfusion Prior to Rectal Surgery for Rectal Tumor or Sigmoid Colon Surgery (AMIREMBOL)

Centre Hospitalier Universitaire de Nīmes

Status

Completed

Conditions

Cancer, Rectum

Cancer, Sigmoid

Treatments

Procedure: Inferior mesenteric artery ligation

Procedure: embolization of the inferior mesenteric artery

Study type

Interventional

Funder types

Other

Identifiers

NCT03628248

2017-A03527-46 (Other Identifier)

NIMAO/2017-02/JF-02

Details and patient eligibility

About

The investigators hypothesize that a primary embolization, 3-4 weeks before surgery, would allow development of vascular collaterality, in particular for the marginal artery which will ensure a better colonic perfusion.

Enrollment

10 patients

Sex

All

Ages

18 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

The patient must have given their free and informed consent and signed the consent form
The patient must be a member or beneficiary of a health insurance plan
The patient is at least 18 years old and less than 80 years old
Patient has rectal cancer or sigmoid colon cancer requiring surgical treatment

Exclusion criteria

The subject is participating in another study, or is in a period of exclusion determined by a previous study
The subject refuses to sign the consent
It is impossible to give the subject informed information
The patient is under safeguard of justice or state guardianship
Patient has a history of abdominal surgery
Patient suffers from a hemostasis disorder (hemophilia, von Willebrand disease, thrombocytopenia) and is on anticoagulant therapy.
Patient whose general condition appears too precarious or is taking corticosteroids or immunosuppressants leading to an unacceptable surgical risk.
Renal insufficiency with clearance <45ml / min
Known allergy to contrast media
Patient who had treatment of the abdominal aorta or its branches Reported pregnancy (the existence of effective contraception will be verified for women of childbearing age).
Anatomical variant at risk or absence of marginal artery highlighted at the time of arteriography.
Abnormality of the superior mesenteric artery
Historic occlusion of the inferior mesenteric artery