Effect of Enhanced Recovery After Surgery(ERAS) After Liver Resection for Primary Liver Cancer

Fudan University

Status: Unknown

Conditions: Carcinoma, Hepatocellular

Treatments: Procedure: Enhanced Recovery After Surgery

Study type: Interventional

Funder types: Other

Identifiers

NCT02644603

H-ERAS-MRCT-1511

Details and patient eligibility

About

The purpose of this study is to evaluate Enhanced Recovery After Surgery(ERAS) protocol versus conventional treatment on patients who underwent liver resection for hepatocellular carcinoma(HCC).

Full description

212 patients are randomly recruited from inpatients of Shanghai Zhongshan Hospital, Eastern Hepatobiliary Surgery Hospital, RenJi Hospital, Anhui Provincial Hospital, Subei People's Hospital of Jiangsu Province and Affiliated Tumor Hospital of Nantong University from February 2016 to July 2016. Randomly assigned about half of the patients to receive Enhanced Recovery After Surgery(ERAS) protocol and the other half to receive conventional treatment. Evaluate the safety and efficacy of the ERAS protocol.

Enrollment: 214 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosed with HCC with indications for surgery
• Without any surgical contraindications
• Under went open liver resection
• Operation ranges less than 4 hepatic segments
• Informed consent

Exclusion criteria

• Not suitable for surgery
• Benign lesions or other lesions proved by pathology
• Surgical procedure changed during operation or combined evisceration
• Refused to participate or drop out

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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214 participants in 2 patient groups

Enhanced Recovery After Surgery

Experimental group

Description:

Patients underwent ERAS protocol

Treatment:

Procedure: Enhanced Recovery After Surgery

Conventional Treatment

No Intervention group

Description:

Patients underwent conventional treatment