Effect of Enhanced Recovery After Surgery (ERAS) on C-reactive and Visceral Proteins (ERASAG)

Jilin University

Status: Completed

Conditions: Gastric Cancer

Treatments: Procedure: ERAS protocols; Procedure: conventional pathway group

Study type: Interventional

Funder types: Other

Identifiers

NCT02348229

2013-212

Details and patient eligibility

About

The investigators designed a prospective randomized, controlled clinical trial then recruited 149 consecutive advanced gastric cancer patients. Further divided into a ERAS group (n=73) and a conventional pathway group (n=76). Surgical technique in both groups was same laparoscopic-assisted gastrectomy with D2 lymphadenectomy. Compared outcomes included clinical parameters and serum indicators.

Full description

Enhanced recovery after surgery combined with laparoscopic-assisted gastrectomy was successfully carried out in this study. Recovery parameters such as the length of time to return to normal diet,mean hospital stay (d) were recorded.

Enrollment: 149 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Age 18-75 years old
2. Diagnosis confirmed by the endoscopic biopsy and total-body CT scan
3. No history of the chronic renal disease ,chronic liver disease, cardiopulmonary dysfunction, ASA score≦3
4. No neoadjuvant chemotherapy and radiotherapy
5. No digestive obstruction and distant metastasis

Exclusion criteria

1. Conversion to open gastrectomy
2. A large amount of bleeding leading(>500ml)
3. Patients withdrew their consent

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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149 participants in 2 patient groups

ERAS group

Experimental group

Description:

ERAS protocols

Treatment:

Procedure: ERAS protocols

Procedure: ERAS protocols

Procedure: ERAS protocols

Procedure: ERAS protocols

Procedure: ERAS protocols

Procedure: ERAS protocols

Procedure: ERAS protocols

Procedure: ERAS protocols

Procedure: ERAS protocols

Procedure: ERAS protocols

Procedure: ERAS protocols

conventional pathway group

Other group

Description:

using conventional pathway

Treatment:

Procedure: conventional pathway group

Procedure: conventional pathway group

Procedure: conventional pathway group

Procedure: conventional pathway group

Procedure: conventional pathway group

Procedure: conventional pathway group