Effect of Enhanced Recovery After Surgery (ERAS) on Inflammatory Response After Planned Abdominal Hysterectomy (GERAS)

Antypin Eduard Eduardovich

Status: Unknown

Conditions: Hysterectomy

Study type: Observational

Funder types: Other

Identifiers

NCT01747005

SMH-0001

Details and patient eligibility

About

The aim of study is to determine effect of enhanced recovery after surgery (ERAS) on inflammatory response after abdominal hysterectomy.

Enrollment: 80 estimated patients

Sex: Female

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Informed consent
• Abdominal hysterectomy
• ASA class I or II

Exclusion criteria

• psychiatric disorders
• ASA III and IV
• Chronic inflammatory disorders
• Pregnancy
• Local anesthetics allergy
• Coagulation disorders
• patients receiving anticoagulants

Trial design

80 participants in 2 patient groups

Conventional therapy

ERAS

Description:

Oral intake of solid food restriction 6 hours before surgery. Oral intake clear fluids restriction 2 hours before surgery. Intravenous 5% Dextrose-500 ml 1 hour before surgery. Intravenous dexamethasone -4mg before anesthesia. Combined spinal-epidural anesthesia. Intraoperatively 10 ml/kg intravenous of crystalloids. Paracetamol intravenous 1g. Early mobilization of patient. Oral solid food intake 4 hour postoperative. Postoperative continuous epidural analgesia.