Effect of Er,Cr:YSGG Sub-Ablative Laser Irradiation on Fissure Caries Prevention in Permanent Molars

Alexandria University

Status: Enrolling

Conditions: Caries,Dental

Treatments: Procedure: Fluoride varnish application; Procedure: sub-ablative Er,Cr:YSGG laser

Study type: Interventional

Funder types: Other

Identifiers

NCT06826456

10556-0008839

Details and patient eligibility

About

Background: Subjecting human dental enamel to sub-ablative laser has been suggested as a novel way of caries prevention. However, further studies are needed to establish its use as a routine clinical procedure for caries prevention.

The aim of this study: This study aims to evaluate the effect of Er,Cr:YSGG subablative laser irradiation on caries resistance of occlusal fissures of permanent molars.

Materials and methods: In-vivo study, a split mouth randomized controlled trial with sixty patients having two fully erupted bilateral first permanent molars (ICDAS-II score 0,1 or 2). The pits and fissures will be subjected to sub-ablative power of Er,Cr:YSGG Laser (Group 1, n=90) and will be compared with fluoride varnish application on the first permanent molars in the same arch(Group 2,n=90). DIAGNOdentTM readings and changes in ICDAS-II score will be assessed at base line and at 3,6,9 and 12 months follow-up.

Enrollment: 60 estimated patients

Sex: All

Ages: 6 to 12 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Participants of age 6-12 years old
• Patients ranking definitely positive or positive on Frankl behavior rating scale
• Having at least two bilateral fully erupted first permanent molars with untreated non-cavitated occlusal surfaces with deep grooves, the included teeth will have International Detection and Assessment System (ICDAS-II)/ severity scores 0, 1 or 2
• Initial DIAGNOdent Score not exceeding value of 25 indicating only enamel involvement
• Patients whom their parents are willing to comply with all study procedures and protocols and will be given an informed consent to participate

Exclusion criteria

• Patients with any known medical history of systemic diseases
• Patients having first permanent molar with hypoplastic or hypocalcified enamel
• Patients using medications that may affect the oral flora or salivary flow
• Patients treated with in-office fluoride treatment within the last 3 months prior to being enrolled in the study.
• Patients showing evidence of poor oral hygiene according to Silness and Löe plaque index

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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60 participants in 2 patient groups

Laser irradiation

Experimental group

Description:

First permanent molars subjected to sub-ablative Er,Cr:YSGG laser

Treatment:

Procedure: sub-ablative Er,Cr:YSGG laser

Fluoride Varnish

Active Comparator group

Description:

First permanent molars subjected to fluoride varnish application

Treatment:

Procedure: Fluoride varnish application