Effect of Erythropoiesis-Stimulating Agent Therapy in Patients Receiving Palliative Care of Chronic Kidney Disease

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The Chinese University of Hong Kong

Status

Completed

Conditions

Anemia of Chronic Kidney Disease

Treatments

Drug: Erythropoiesis-Stimulating Agent

Study type

Observational

Funder types

Other

Identifiers

NCT03427801
CREC2017.147

Details and patient eligibility

About

An observational study to evaluate the effect of erythropoiesis-stimulating agents in treating anaemia of renal disease among adult patients receive palliative care instead of dialysis.

Full description

Erythropoiesis-stimulating agent (ESA) has been commonly used to manage patients with end-stage renal disease receiving dialysis. The effects of ESA, however, are unclear. This study compares the result of erythropoiesis-stimulating agent (ESA) versus supportive care for chronic kidney disease patients receiving palliative care. The investigators design a retrospective observational study to evaluate the effect of erythropoiesis-stimulating agents in treating anaemia of renal disease among adult patients receive palliative care instead of dialysis. The primary objective is to assess whether ESA can reduce the transfusion burden and hospitalization.

Enrollment

78 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • patients aged 18 years and older, who opted for ESA treatment during palliative renal care for > 360 days between January 1, 2014 and December 31, 2016

Exclusion criteria

  • patients who had dialysis or kidney transplant treatment

Trial design

78 participants in 2 patient groups

Treatment Group
Description:
Chronic kidney disease patient receiving palliative care and erythropoiesis-stimulating agent
Treatment:
Drug: Erythropoiesis-Stimulating Agent
Control Group
Description:
Chronic kidney disease patient receiving palliative care without erythropoiesis-stimulating agent

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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