Effect of Etomidate and Propofol on Electroencephalography (CHAPE)

Air Force Military Medical University of People's Liberation Army

Status: Unknown

Conditions: General Anesthesia

Treatments: Drug: etomidate anesthesia; Drug: propofol anesthesia

Study type: Interventional

Funder types: Other

Identifiers

NCT04369014

XJH-A-20200330

Details and patient eligibility

About

Electroencephalography (EEG) monitoring reflect the brain electro-activity. Different anesthetics may show different changes in EEG during anesthesia. Etomidate and propofol are widely used for general anesthesia. The characteristic changes of these two anesthetics may be different.

Enrollment: 68 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients scheduled for surgery under general anesthesia
• Patients provided written informed consent

Exclusion criteria

• Patients with history of neurological or psychiatric diseases
• Patients younger than 18 years old
• Patients scheduled for surgery involved head
• Patients with pregnancy or planned for breeding

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

---

68 participants in 2 patient groups

etomidate

Experimental group

Treatment:

Drug: etomidate anesthesia

propofol

Experimental group

Treatment:

Drug: propofol anesthesia