Effect of Exercise on Cognitive Function and Mental Health in Heroin Addicts

Guangzhou Sport University

Status: Completed

Conditions: Heroin Addicts; Negative Thinking/Affect; Unspecified Symptoms and Signs Involving Cognitive Functions Following Unspecified Cerebrovascular Disease; Executive Function

Treatments: Behavioral: Aerobic exercise; Resistance exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT05650983

2022LcLL-30

Details and patient eligibility

About

The goal of this [type of study: exercise intervention study] is to test in describe participant health conditions. The main questions it aims to answer are:

• [Whether physical exercise improves executive function of male heroin addicts]
• [Whether physical exercise improves negative thinking/affect psychological experience of male heroin addicts] Participants will be randomly selected for medium-intensity strength training (resistance exercise,n=30), 30 will be selected for 1-hour long balloon volleyball sessions (aerobic exercise) at 60-70% volume of oxygen uptake during peak exercise, weekly 5 times for 12 weeks; and 30 will be assigned to the no-exercise control group, Participants will perform Executive function tests and the Symptom Checklist-90 Revised questionnaire at pre and post intervention.

Researchers will compare resistance exercise group,aerobic exercise group and no-exercise control group to see if effects of exercise on executive function and negative thinking/affect psychological experience of male heroin addicts.

Enrollment: 90 patients

Sex: Male

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• were men who met the Manual of Mental Disorders (DSM)-IV criteria for current heroin dependence

Exclusion criteria

• any major mental illness other than heroin addiction
• any exercise taboo

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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90 participants in 2 patient groups

1.Aerobic exercise

Experimental group

Description:

play balloon volleyball for Aerobic exercise and aimed at maximizing the strain on the cardiovascular system (60-70% of heart rate recovery). Aerobic exercise intervention five times a week, one hour each time，for three months.

Treatment:

Behavioral: Aerobic exercise; Resistance exercise

2.Resistance exercise

Experimental group

Description:

Resistance strength training for Resistance exercise and aimed at promoting the greatest hypertrophy response(65% of 1 repetition maximum and repeated up to 15 times). Resistance exercise intervention five times a week, one hour each time,for three months.

Treatment:

Behavioral: Aerobic exercise; Resistance exercise