Effect of Exercise on Heart Function in Healthy Elderly People

Norwegian University of Science and Technology

Status: Completed

Conditions: Diastolic Dysfunction

Treatments: Other: Aerobic interval training

Study type: Interventional

Funder types: Other

Identifiers

NCT00804518

4.2008.2177

Details and patient eligibility

About

The purpose of this study is to determine the effect of aerobic interval training on left- and right ventricular diastolic- and systolic function on healthy, sedate people over 70 years. The old sedate cohort will be compared to young, sedate subjects also performing aerobic interval training and old master athletes without intervention.

Full description

Aging is associated with a reduced diastolic and systolic function of the heart. Earlier studies have shown that physical exercise can improve both systolic and diastolic function. However the impact on age-related cardiac function is to some extent conflicting. The use of different training intensities will impact on the cardiac result. We have in earlier studies shown aerobic interval training at 90 % of maximal heart rate (4x4 minutes) to have more impact on cardiac function, endothelial function and maximal oxygen uptake compared to moderate intensity.

To our knowledge the effect of aerobic interval training on cardiac function has not been studied in an old, sedate group before.

Enrollment: 45 patients

Sex: All

Ages: 70+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• over 70 years, healthy
• not exercising more than twice per week

Exclusion criteria

• chronic illness
• chronic use of any medication
• regular smoking
• metabolic or cardiovascular diseases

Trial design

Primary purpose: Prevention

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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45 participants in 1 patient group

Exercise intervention

Experimental group

Treatment:

Other: Aerobic interval training