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Effect of Exercise on Metabolic Health

University of Michigan logo

University of Michigan

Status

Completed

Conditions

Obesity

Treatments

Other: Exercise

Study type

Interventional

Funder types

Other

Identifiers

NCT02001142
ADA 7-13-TS-35

Details and patient eligibility

About

One of the main objectives of this study will be to assess potential differences in important risk factors associated with Metabolic Syndrome in overweight adults who do not participate in a regular exercise program compared with overweight individuals who do exercise regularly. In addition, we will determine the effects of a single, modest session of exercise on the body's ability to control blood sugar and regulate fat metabolism in obese sedentary adults vs. obese adults who live a physically active lifestyle. Our study focuses on identifying mechanisms responsible for improved insulin action related to regular exercise and to provide novel targets for preventing and treating type 2 diabetes.

Enrollment

15 patients

Sex

All

Ages

18 to 40 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Body Mass Index [BMI] = 30-45 kg/m2, fasting blood glucose concentration must be < or = to125 mg/dl, Hematocrit > or = to 34%, all women must be pre-menopausal

Exclusion criteria

  • pregnancy or actively breastfeeding, weight instability (> or = to ± 5 lbs in the past month) evidence of cardiovascular or metabolic diseases, taking medications know to affect lipid and/or glucose metabolism.

Trial design

Primary purpose

Basic Science

Allocation

Randomized

Interventional model

Single Group Assignment

Masking

None (Open label)

15 participants in 2 patient groups

Exercise
Experimental group
Treatment:
Other: Exercise
Sedentary Control
No Intervention group

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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