Effect of Exercise on Renal Function in Predialysis

King's College Hospital NHS Trust

Status and phase

Completed

Phase 2

Phase 1

Conditions

Chronic Kidney Disease

Treatments

Other: Exercise

Study type

Interventional

Funder types

Other

Identifiers

NCT02155036

KCH11-123

Details and patient eligibility

About

The proposed research aims to examine whether regular aerobic exercise can preserve renal function, improve aerobic capacity, physical and psychosocial function, strength, cardiovascular function, general well-being and quality of life. Ultimately, the research aims to prove that exercise is a more cost-effective and a more efficient use or healthcare resources used in the treatment of patients with CKD. Exercise is a relatively cheap treatment option which is readily available and accessible for this patient population. establish if, compared with usual care, an exercise programme for pre-dialysis CKD patients;

Preserves renal function.
Improves aerobic capacity, physical and psychosocial function, strength, cardiovascular function, general well-being and quality of life.

Enrollment

20 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

- Stages 3-4 chronic kidney disease (CKD) patients (glomerular filtration rate (GFR) 20-60 mL/min)
Male or female
Aged >18 years
Written informed consent

Exclusion criteria

Pregnancy
- Requiring support for ambulation less than 20m
- Vasculitis,
- Proliferative diabetic retinopathy,
- Severe osteodystrophy,
- Uncontrolled diabetes,
- Psychiatric illness, including anxiety, mood and untreated eating disorders
- Infection or course of antibiotics within the last month