Effect of Exercise Training on Salivary Immunoglobulin A in Patients With Chronic Obstructive Pulmonary Disease

Bayside Health

Status: Completed

Conditions: COPD

Treatments: Other: Pulmonary rehabilitation

Study type: Interventional

Funder types: Other

Identifiers

NCT04604717

110314

IBAS110314 (Other Grant/Funding Number)

Details and patient eligibility

About

The purpose of this study is to determine whether whole body exercise training alters the immunity in the lungs of people with COPD and reduces the incidence of chest infections over the longer term.

Full description

Patients will undertake an 8 weeks pulmonary rehabilitation program of exercise and education. Those who decline to take part in pulmonary rehabilitation will have the same outcome measures collected at the same timepoints.

Enrollment: 35 patients

Sex: All

Ages: 40 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosis of COPD (FEV1/FVC < 70), smoking Hx of minimum of 10 pack years

Exclusion criteria

• Diagnosis of asthma, bronchiectasis, attendance at pulmonary rehabilitation within last 12 months, exacerbation of COPD within last 4 weeks

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

35 participants in 2 patient groups

Pulmonary rehabilitation

Experimental group

Description:

8 weeks of pulmonary rehabilitation (twice weekly training) Exercise and education sessions accompanied by home exercise program

Treatment:

Other: Pulmonary rehabilitation

Control group

No Intervention group

Description:

Usual medical treatment for 8 week period