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Body size and eye function play an essential role in adapting to the environment and human survival. Growth hormone is commonly recognized by its effect on the height of individuals; Although from an evolutionary perspective, the effects of growth hormone on eye development are more important. Although the effect of growth hormone on eye development has not been accurately determined, the results of a number of studies suggest the effect of growth hormone on eye development.
Despite the large number of studies that have investigated the effects of growth hormone on height growth, there are few studies that have investigated the effects of growth hormone on the eye.
To the best of our knowledge, no study has been conducted to investigate the effect of growth hormone on ocular findings of patients with early or precocious puberty. Therefore, we intend to investigate the effect of growth hormone on ocular findings of patients with early or precocious puberty.
Full description
Investigators will achieve the following data from the participants:
Demographics
Past medical history
Bone and calendar age
4- Stage of puberty
5- Ocular examination
Enrollment
Sex
Ages
Volunteers
Inclusion criteria
Sample group (with early or precocious puberty):
Children with precocious puberty based on Tanner classification
Girls 4 to 10 years old
Boys aged 4 to 11
No known eye problems including: history of eye trauma, eye surgery 5- lack of family history of glaucoma or increased intraocular pressure
Lack of previous history of receiving growth hormone 7. Lack of systemic disease or known syndromes 8. Consent to participate in the study
Exclusion criteria
90 participants in 3 patient groups
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Central trial contact
Mohsen Pourazizi, MD
Data sourced from clinicaltrials.gov
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