Effect of External Oblique Intercostal Block Versus Paravertebral Block on Postoperative Pain and Complications in Open Nephrectomy Patients

Hacettepe University

Status: Enrolling

Conditions: Pain Scores; Nephrectomy; External Oblique Intercostal Block; Paravertebral Block

Treatments: Drug: Diclofenac; Drug: morphine; Drug: Bupivacaine; Drug: paracetamol

Study type: Interventional

Funder types: Other

Identifiers

NCT07071012

KA-24040

Details and patient eligibility

About

This study aims to compare the effects of external oblique intercostal block versus paravertebral block on postoperative pain and complications in patients undergoing open nephrectomy.

Enrollment: 98 estimated patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Aged 18 to 90 years
• Stage 2 renal cell carcinoma scheduled for open radical nephrectomy without lymph node dissection
• ASA classification I-III
• Mini-Mental State Examination score ≥24
• Provided written informed consent

Exclusion criteria

• Neuropathy
• Hepatic failure
• Coagulopathy
• Local anesthetic allergy
• Mini-Mental State Examination score <24
• Refusal to participate

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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98 participants in 2 patient groups

Paravertebral block

Active Comparator group

Description:

Patients scheduled to undergo thoracic paravertebral block will receive an injection of 20 ml of 0.25% bupivacaine hydrochloride into the paravertebral space between the parietal pleura and the costotransverse ligament using a block needle under ultrasound guidance.

Treatment:

Drug: paracetamol

Drug: Bupivacaine

Drug: morphine

Drug: Diclofenac

External Oblique Intercostal Block

Active Comparator group

Description:

Patients scheduled to undergo an external oblique intercostal block will receive an injection of 30 ml of 0.25% bupivacaine hydrochloride between the external oblique muscle and the intercostal muscle at the level of the 6th rib, using a block needle under ultrasound guidance.

Treatment:

Drug: paracetamol

Drug: Bupivacaine

Drug: morphine

Drug: Diclofenac