Effect of Extracorporeal Shock Wave in the Treatment of Knee Osteoarthritis

Peking University

Status: Unknown

Conditions: Cartilage Injury; Knee Osteoarthritis

Treatments: Device: shock wave device

Study type: Interventional

Funder types: Other

Identifiers

NCT03962270

M2018089

Details and patient eligibility

About

In this study, the effectiveness of ESWT in the treatment of knee OA was investigated from the perspective of cartilage injury，and to prove that shockwave could delay the early and middle stage OA progression by improving cartilage condition

Enrollment: 36 estimated patients

Sex: All

Ages: 40 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Knee joint ROM normal or near normal: flexion 110 ° or reach 0 ° or less
• MR prompt exist cartilage damage, there is no lack of full-thickness cartilage
• Kellgren - Lawrence (K - L) grade II - III grade
• The international association of cartilage repair cartilage damage grading system (ICRS) class I - III
• Informed consent and sign relevant documents
• Follow doctor's instructions and follow up on time

Exclusion criteria

• Metabolic arthritis
• Trauma of bone joint
• Inflammatory diseases
• Previous knee surgery history
• History of knee cavity injection in the past 6 months
• Serious cardiovascular diseases, pulmonary diseases or other serious diseases affecting survival, etc

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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36 participants in 2 patient groups

Treatment group

Experimental group

Treatment:

Device: shock wave device

Control group

Sham Comparator group

Treatment:

Device: shock wave device