Effect of Fan Application in Preventing Ticagrelor-Associated Dyspnea (ACS)

Acibadem University

Status: Enrolling

Conditions: Dyspnea; Ticagrelor; Acute Coronary Syndromes

Treatments: Other: STANDART CARE; Other: STANDART CARE & FAN THERAPY

Study type: Interventional

Funder types: Other

Identifiers

NCT07268859

Is an identifier other (Other Identifier)

ATADEK2024-10/449

Details and patient eligibility

About

This study will be conducted in the coronary intensive care unit of Dr. Siyami Ersek Chest, Heart and Vascular Surgery Training and Research Hospital. It aims to investigate the effect of hand fan therapy on ticagrelor-associated dyspnea in patients receiving ticagrelor.

Full description

Patients in the coronary intensive care unit receiving ticagrelor and meeting the inclusion criteria will be included. The study includes two groups: a control group receiving standard care and an experimental group receiving standard care plus hand fan therapy. A total of 110 participants (55 per group) will be recruited. Randomization will be performed using a computer-based randomization program. Due to the nature of the intervention and sample characteristics, participants and the researcher will not be blinded. Data will be analyzed by a statistician not involved in the study, and the findings will be reported.

Enrollment: 110 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Between the ages of 18 and 65,
• No severe hearing and vision problems,
• Can speak and understand Turkish,
• Easy to communicate with,
• First-time sufferer of acute coronary syndrome (ACS) for the first time,
• Decided to start ticagrelor therapy,
• Able to adapt to treatment,
• Individuals who volunteered to participate in the research.

Exclusion criteria

• Having any problem that prevents you from communicating cognitively, emotionally and verbally,
• Obstructive sleep abnormalities,
• Have a disease that affects respiratory function (stage IV cancer, bronchial asthma, COVID-19, lung cancer, pulmonary edema, chronic obstructive pulmonary disease, pulmonary hypertension, pulmonary embolism, pneumonia or bronchitis, etc.),
• With metabolic abnormalities,
• Intubated after the procedure,
• Previously treated with ticagrelor,
• Individuals who did not volunteer to participate in the study. Losses to follow up
• Individuals who wish to leave the study voluntarily.
• Saturation value below 95%,
• The one with the arrest,
• Who will not be able to fulfill the requirements of the work,
• Individuals with life-threatening conditions

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

110 participants in 2 patient groups

Standard Care (Control Group)

Active Comparator group

Description:

Routine ward care including semi-Fowler position and breathing exercises. Standard institutional care will be applied. Presence, number, and severity of dyspnea attacks will be recorded during the first 2 hours after ticagrelor administration.

Treatment:

Other: STANDART CARE

Standard Care + Fan Therapy (Experimental Group)

Experimental group

Description:

In addition to standard care, patients will undergo hand fanning for 5 minutes at 30, 60, and 120 minutes after ticagrelor administration. The fan will be directed toward the patient's face from a distance of \~15 cm. Dyspnea severity and number of episodes will be recorded during this period. Device: Hand Fan

Treatment:

Other: STANDART CARE & FAN THERAPY