Effect of Feeding Frequency on Glucose and Insulin Metabolism and Substrate Partitioning

Maastricht University Medical Centre (MUMC)

Status: Completed

Conditions: Insulin; Glucose Metabolism

Treatments: Dietary Supplement: High feeding frequency (14x); Dietary Supplement: low feeding frequency (3x)

Study type: Interventional

Funder types: Other

Identifiers

NCT01034293

MEC 09-3-032

Details and patient eligibility

About

The purpose of this study is to determine the effect of feeding frequency on glucose and insulin metabolism and substrate partitioning.

Enrollment: 14 patients

Sex: Male

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• BMI: 18.5-25 kg/m2 (lean)
• Gender: Male
• Age: subjects has to be older than 18 and including 35 years old
• Caucasian

Exclusion criteria

• Metabolic abnormalities such as:

  1. Lactose intolerant
  2. Diabetes Mellitus
  3. Hypertension
  4. Hypotension
  5. Cardiovascular diseases
  6. Asthma and other obstructive pulmonary diseases
  7. Elevated fasting blood glucose level

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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14 participants in 2 patient groups

low feeding frequency (3x)

Experimental group

Treatment:

Dietary Supplement: low feeding frequency (3x)

High feeding frequency (14x)

Experimental group

Treatment:

Dietary Supplement: High feeding frequency (14x)