Effect of Fentanyl on Pain Severity and Duration of Labor

Mashhad University of Medical Sciences

Status and phase: Terminated; Phase 3; Phase 2

Conditions: Decrease Labor Pain

Treatments: Drug: Fentanyl

Study type: Interventional

Funder types: Other

Identifiers

NCT01648595

Effect of Fentanyl

Details and patient eligibility

About

Background: There are two methods of pharmacologic and non- pharmacologic for reducing pain of delivery. It is necessary to be known effect of these drugs on the mother and fetus during labor adverse. Therefore, the purpose of this study was determination of effect of Fentanyl intravenously on pain severity during the active phase of labor.

Sex: Female

Ages: 21 to 37 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• multiparas pregnant women (gravid 2-7),
• term singleton pregnancy,
• cephalic presentation,
• low risk pregnancy with no history of drug tolerance (addiction),
• medical and mental diseases.

Exclusion criteria

• Respiratory rate ≤ 8 or maternal bradycardia (pulse rate less than 60).

Trial design

Primary purpose: Supportive Care

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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70 participants in 2 patient groups

Fentanyl

Experimental group

Description:

In case group, 50 micrograms fentanyl was prescribed in two doses with an interval of 1 hour. In control group was not intervention.

Treatment:

Drug: Fentanyl

Without Fentanyl

No Intervention group

Description:

The control group did not receive Fentanyl.