Effect of Fentanyl With Topical Levobupivacaine With Nasal Packing in Endoscopic Nasal Surgery (fentanyl)

Assiut University

Status and phase: Unknown; Phase 2

Conditions: Analgesia During Removal of Nasal Pack After Nasal Surgery

Treatments: Drug: Fentanyl + Topical Levobupivacaine; Drug: levobupivacaine

Study type: Interventional

Funder types: Other

Identifiers

NCT04410588

marwawael

Details and patient eligibility

About

the Investigators aim to study the effect of fentanyl with topical levobupivacaine with nasal packing in endoscopic nasal surgery

Enrollment: 75 estimated patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:1. All patients in the age of 18-60 year 2. ASA I-II 3. Undergoing elective nasal endoscopic surgery

Exclusion Criteria:

1. Patients will also be excluded if any perioperative cardiovascular or respiratory event occurred which the anaesthetist with clinical responsibility for the patient thought would make the study intervention clinically unacceptable.
2. unsatisfactory preoperative peripheral arterial oxygen saturation.
3. Unsatisfactory preoperative hemoglobin level.
4. Neurological or psychiatric disease.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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75 participants in 3 patient groups

saline

No Intervention group

Description:

saline for pain for nasal packing

levobupivacaine

Active Comparator group

Description:

levobupivacaine for pain of nasal packing

Treatment:

Drug: levobupivacaine

fentanyl +levobupivacaine

Active Comparator group

Description:

fentanyle with levobupivacaine for pain of nasal packing

Treatment:

Drug: Fentanyl + Topical Levobupivacaine