Effect of Flixweed and Fig on Irritable Bowel Syndrome With Predominant Constipation: a Single Blind Randomized Clinical Trial.

Isfahan University of Medical Sciences

Status: Completed

Conditions: Irritable Bowel Syndrome Predominant Constipation

Treatments: Other: Ficus carica; Other: Descurainia Sophia

Study type: Interventional

Funder types: Other

Identifiers

NCT02559245

[e-mail]

Details and patient eligibility

About

This study evaluates effect of Ficus carica and Descurainia Sophia on irritable bowel syndrome predominant constipation. one-third of patients will receive Ficus carica, another one-third will receive Descurainia Sophia and remained patients only will follow their regular diet for 4 months.

Enrollment: 150 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• patients with irritable bowel syndrome predominant constipation

Exclusion criteria

• Subjects with significant cardiovascular, renal, hepatic, pulmonary, endocrine, metabolic, hematologic disorders,
• structural abnormalities of the gastrointestinal tract or
• diseases ⁄conditions that affected bowel transition,
• surgery,
• any prokinetic or laxative drug used during the past month,
• any medication that may affect gastrointestinal motility,
• other therapeutic dietary advice for IBS,
• used Fig or Flixweed during the last month,
• diarrhea,
• pregnancy or
• breast-feeding

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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150 participants in 3 patient groups

Ficus carica

Experimental group

Description:

45 grams Ficus carica before breakfast and lunch with 1 glass of water every day respectively (total consumption: Ficus carica 90g/d)

Treatment:

Other: Ficus carica

Descurainia Sophia

Experimental group

Description:

30 grams Descurainia Sophia before breakfast and lunch with 1 glass of water every day respectively (total consumption: Descurainia Sophia 60g/d)

Treatment:

Other: Descurainia Sophia

controled

No Intervention group

Description:

participants will follow their usual diet