Effect of Follicle Flushing on Oocyte Fertilization Rate

Eugonia

Status: Unknown

Conditions: Infertility

Treatments: Procedure: intracytoplasmic sperm injection (ICSI)

Study type: Observational

Funder types: Other

Identifiers

NCT03353285

number of flushes

Details and patient eligibility

About

The purpose of this study is to investigate the impact of follicular flushing on fertilization rate in women undergoing IVF treatment

Full description

This will be a prospective observational study on the effect of follicular flushing on fertilization rate in women undergoing IVF treatment.

Oocytes from each woman will be allocated to one of three groups, depending on the aspirate or flush they are recovered from:

Group I= egg retrieved in the follicular fluid of the first aspirate (no flushing) Group II= egg retrieved in the 1st-2nd flush Group III= egg retrieved in the 3rd-5th flush

development and utilization. Pregnancy rates will be reported as a surrogate outcome.

Enrollment: 60 estimated patients

Sex: Female

Ages: 18 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Up to 40 years old
• Both ovaries present
• Triggering final oocyte maturation using hCG or GnRH agonist

Exclusion criteria

• Egg donation
• PGD cases

Trial design

60 participants in 3 patient groups

Group I

Description:

Group I= egg retrieved in the follicular fluid of the first aspirate (no flushing)

Treatment:

Procedure: intracytoplasmic sperm injection (ICSI)

Group II

Description:

Group II= egg retrieved in the 1st-2nd flush

Treatment:

Procedure: intracytoplasmic sperm injection (ICSI)

Group III

Description:

Group III= egg retrieved in the 3rd-5th flush

Treatment:

Procedure: intracytoplasmic sperm injection (ICSI)