Effect of Functional Endoscopic Sinus Surgery On Eustachian Tube Function in Patients With Nasal Polypi


Assiut University




Functional Endoscopic Sinus Surgery


Device: Endoscope

Study type


Funder types




Details and patient eligibility


This study is conducted to : Correlate the incidence of ETD with nasal polypi. To evaluate the effects of functional endoscopic sinus surgery on eustachian tube function in patients with nasal polypi

Full description

Eustachian tube dysfunction (ETD) is a frequently applied diagnosis, used when abnormal ET function is believed to underlie any of a wide range of symptoms or middle ear (ME) abnormalities. Two distinct forms of the disorder are recognised, representing different ends of the spectrum of ET function: 1)obstructive ETD (OETD), in which tubal opening or patency is reduced, and 2) patulous ETD (PETD), in which the ET is too open. It has been suggested that some patients with OETD have either predominantly active dysfunction (failure of muscle-controlled opening), or passive dysfunction (failure of pressure-related opening). There are several explanations to account for the ET dysfunction associated with nasal diseases: Mechanical obstruction of ET orifice may occur due to nasal mass. Increased secretions from seromucous glands in the pharyngeal portion of ET may accumulate and block the tube. Lymphatic stasis due to edema of the submucosa of the tube resulting in compromise of the lumen may produce ET dysfunction. Further increase in hydrostatic pressure result in the accumulation of ME fluid by transudative process. Tubal dysfunction may be related to deficiency of surfactant that is thought to facilitate tubal opening. It has been postulated that this material is inactivated by inflammation. ETD symptoms will decrease post-endoscopic sinus surgery to a level comparable with a non-CRS population The use of the ETDQ-7 has the potential to enhance clinical care by highlighting the impact of ETD as well as guiding and evaluating appropriate management. Further prospective testing of


50 estimated patients




No Healthy Volunteers

Inclusion criteria

Patient Who have been diagnosed to have nasal polypi Both unilateral and bilateral before doing FESS

Exclusion criteria

children Patient. Patients with craniofacial abnormalities or active infection Patients with suspected nasal and nasopharyngeal tumour Patients with nasal and ear surgery

Trial contacts and locations



Central trial contact

Safia Sh Abd-Ellattef, 3; Mohamed Ad Mahmoud, 2

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location


© Copyright 2024 Veeva Systems