Effect of Galactose Ingestion on Postprandial Lipemia

University of Bath

Status: Completed

Conditions: Lipemia; Cardiovascular Risk Factor

Treatments: Dietary Supplement: Galactose; Dietary Supplement: Glucose

Study type: Interventional

Funder types: Other

Identifiers

NCT03439878

MSES 16/17-011

Details and patient eligibility

About

This study aims to assess the postprandial triglyceride response to the ingestion of a high-fat meal with co-ingestion of either galactose, or glucose.

Enrollment: 10 patients

Sex: Male

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Male
• 18 to 35 years old
• Body mass index <30 kg/m2

Exclusion criteria

• Female
• Body mass index >29.9 kg/m2
• Any history of metabolic disease
• Allergies or intolerances to milk and/or cream

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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10 participants in 2 patient groups

Galactose

Experimental group

Description:

Ingestion of 0.75 g/kg body mass of d-galactose monohydrate co-ingested with cream to provide 1 g/kg body mass of fat.

Treatment:

Dietary Supplement: Galactose

Glucose

Active Comparator group

Description:

Ingestion of 0.75 g/kg body mass of dextrose monohydrate co-ingested with cream to provide 1 g/kg body mass of fat.

Treatment:

Dietary Supplement: Glucose