Effect of Game Based Approach on Oxygenation, Functional Capacity and Quality of Life in Primary Ciliary Dyskinesia

Hacettepe University

Status: Completed

Conditions: Kartagener Syndrome; Primary Ciliary Dyskinesia; Immotile Cilia Syndrome

Treatments: Other: Game and home based therapy; Other: Home based therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT03832491

KA-180026

Details and patient eligibility

About

Impaired pulmonary function, decreased physical activity, functional capacity and depending on these factors are reported in patients with primary ciliary dyskinesia in recent studies. The purpose of this study to evaluate the effects of game based approach on pulmonary function, functional capacity and quality of life in patients with primary ciliary dykinesia.

Full description

Primary ciliary dyskinesia (PCD) is an autosomal recessive hereditary disorder characterized by congenital structural abnormalities and impairment of respiratory function. Mucociliary clearance is affected by disorders in the structure and movement of cilia. That causes repeated infections in the upper and lower respiratory tract.In addition to mucociliary effects and impaired lung function, it is thought that there may be a decrease in respiratory muscle strength and functional capacity. One of the factors affecting functional capacity is the level of physical activity. For these reasons, the management of the respiratory system in patients with PCD is very important. In addition to airway clearence techniques, approaches to increase physical activity are also important. It was thought that severe physical activity could be an important determinant of cardiopulmonary functional capacity in patients with mild to moderate PCD. The level of physical activity is known to be associated with quality of life.

In literature no study investigated the effects of game based approach on oxygenation, functional capacity and quality of life in patients with PCD. Game based approach is a new method lead to increase physical activity. In literature there is no study investigated the effects of game based approach on oxygenation, functional capacity and quality of life in patients with PCD.

Enrollment: 32 patients

Sex: All

Ages: 6 to 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Being diagnosed with PCD
• Being clinically stable
• Between 6-18 years old
• Volunteer to participate in research

Exclusion criteria

• Not having a stable clinical condition
• Patients with severe neuromuscular, musculoskeletal and rheumatological problems
• Patients with loss of balance
• Not being cooperative

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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32 participants in 2 patient groups

Control Group

Other group

Description:

Home Based Therapy: 16 patients with PCD Airway clearence techniques, everday of the week, during eight weeks

Treatment:

Other: Home based therapy

Game and home based therapy group

Experimental group

Description:

Game based approach programme: 16 patients with PCD Game based approach programme will be done using the exergame with the game console, fourty minutes three times per week for eight weeks. Exergame includes five games selected from two kinects games CD. Each game will be played for five games set. Airway clearence techniques, everday of the week, during eight weeks

Treatment:

Other: Game and home based therapy