Effect of Ganglionar Electrical Stimulation on Central Arterial Pressure

University of Brasilia

Status: Completed

Conditions: Chagas Disease; Heart Failure

Treatments: Device: Placebo; Device: TENS

Study type: Interventional

Funder types: Other

Identifiers

NCT01874795

071/2011

Details and patient eligibility

About

This study will evaluate the applications of ganglionar electrical stimulation in patients with Chagas Disease and Ischemic Heart Failure patients.

Full description

A Crossover Randomized Controlled Study will be developed with 3 groups: Healthy Older, Ischemic Heart Failure and Chagas Disease. This individuals will be randomized in two groups: TENS and placebo (same stimulus without electrical output) with 48 hrs between the interventions.

Enrollment: 30 patients

Sex: All

Ages: 40 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Ischemic and Chagas disease previously diagnosticated
• Age above 40 years old

Exclusion criteria

• No vascular disease
• No recent surgery
• No recent infections

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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30 participants in 2 patient groups

Ganglionar Electrical Stimulation

Experimental group

Description:

TENS intervention consisted of continuous flow, symmetrical and rectangular TENS biphasic pulses. The frequency ofstimulation was 80 Hz and the pulse duration was 150 μs, with the intensity in adjusted to the point of muscle contraction.

Treatment:

Device: TENS

Placebo

Sham Comparator group

Description:

The frequency of stimulation was 80 Hz and the pulse duration was 150 μs, equipment did not provide stimulation current.

Treatment:

Device: Placebo