Effect of Garlic Tablet Some Indicators Related to Atherosclerosis

Shahid Beheshti University

Status: Completed

Conditions: Coronary Artery Disease

Treatments: Dietary Supplement: Garlic

Study type: Interventional

Funder types: Other

Identifiers

NCT01948453

513

Details and patient eligibility

About

The purpose of this study is to determine whether garlic in adjunct to conventional medical treatment is effective in improving carotid intima media thickness (CIMT), Flow mediated dilation (FMD) and plasma lipid profile or c-reactive protein of coronary artery disease (CAD) patients.

Enrollment: 56 patients

Sex: All

Ages: 25 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• angiography confirmed coronary artery disease
• lack of consistent use of the garlic in the last month

Exclusion criteria

Change in type of medication during study

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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56 participants in 2 patient groups, including a placebo group

Garlic

Active Comparator group

Description:

daily consumption of two odor controlled garlic tablets

Treatment:

Dietary Supplement: Garlic

Placebo

Placebo Comparator group

Description:

daily consumption of placebo