Effect of Gastrectomy and Anastomosis on Diabetes and Hypertension in Early Gastric Cancer Patients

National Cancer Center (NCC)

Status: Completed

Conditions: Early Gastric Cancer

Treatments: Procedure: gastrectomy; Procedure: Endoscopic submucosal dissection

Study type: Observational

Funder types: Other

Identifiers

NCT01643811

1210552-1

Details and patient eligibility

About

The purpose of this study is to determine whether the extent of gastrectomy and anastomosis type affect chronic metabolic disease such as diabetes and hypertension in early gastric cancer patients.

Enrollment: 159 patients

Sex: All

Ages: 20 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Histologically proven primary gastric adenocarcinoma
• clinical stage Ia or Ib examined with endoscopy, endoscopic ultrasound, and computed tomography
• aged 20-80 year old,
• performance status (PS) of 0 or 1 on Eastern Cooperative Oncology Group (ECOG) scale
• diagnosed as diabetes or hypertension
• patients planning to undergo gastrectomy or endoscopic submucosal dissection
• written informed consent

Exclusion criteria

• having high risk for operation such as severe heart disease, severe respiratory disease
• pregnant
• previous abdominal surgery or radiation therapy
• proven more advanced disease than pathological stage II requiring adjuvant chemotherapy

Trial design

159 participants in 2 patient groups

Gastrectomy

Description:

Patients who underwent gastrectomy for early gastric cancer

Treatment:

Procedure: gastrectomy

Endoscopic submucosal dissection

Description:

Patients who underwent endoscopic submucosal dissection for early gastric cancer

Treatment:

Procedure: Endoscopic submucosal dissection