Effect of General Anesthesia on Early Postoperative Cognitive Function in Cesarean Section

Beni-Suef University

Status: Completed

Conditions: Cesarean Section Complications; Anesthesia Morbidity

Treatments: Other: Assessment document

Study type: Observational

Funder types: Other

Identifiers

NCT03818009

Beni-Suef 17

Details and patient eligibility

About

Cognitive dysfunction is the impairment of the mental process of perception, memory and information processing. The preoperative cognitive state is important, as mild cognitive impairment may be worsened following a cesarean section. Our study will aim to assess the incidence of early cognitive dysfunction after elective and emergent cesarean section under general anesthesia.

Full description

Mechanisms that lead to cognitive decline after anesthesia and surgery remain still unclear and mixed. Some studies suggested that an important role is played by the immune response to surgery. The inflammatory response could contribute to the development of postoperative cognitive decline (POCD0 through secretion of cortisol, cytokines, and other inflammatory mediators. Comparing the effects of general and spinal anesthesia on pregnant patients undergoing an elective cesarean section, found no cognitive change after both anesthesias. Our observational comparative study will be carried out at Beni Suef University Hospital. We will compare early cognitive functions undergoing general anesthesia in patients undergoing elective and emergency cesarean section.

Enrollment: 58 patients

Sex: Female

Ages: 25 to 35 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Women in reproductive age period between 25 and 35 years
• Women booked for an elective or emergency cesarean section.

Exclusion criteria

• Mental disorder preoperative
• Medical conditions ( as Hypertension or diabetes or cardiac diseases)

Trial design

58 participants in 2 patient groups

women undergoing elective CS under general anesthesia

Description:

Early postoperative assessment of the cognitive function of patients through evaluation document which will be filled by the anesthesiologist.

Treatment:

Other: Assessment document

women undergoing emergency CS under general anesthesia

Description:

Early postoperative assessment of the cognitive function of patients through evaluation document which will be filled by the anesthesiologist.

Treatment:

Other: Assessment document