Effect of Gluten Free Diet in Patients With Burning Mouth Syndrome

Institute of Hospitalization and Scientific Care (IRCCS)

Status: Unknown

Conditions: Burning Mouth Syndrome

Treatments: Dietary Supplement: Gluten Free Diet; Dietary Supplement: Normal Diet

Study type: Interventional

Funder types: Other

Identifiers

NCT01867151

BMS2013

Details and patient eligibility

About

Gluten free diet (GFD) is now being tested in patients affected by schizophrenia, autism and multiple sclerosis, making GFD a possible therapeutic weapon not only for celiac disease or gluten sensitivity. In this protocol we investigate the effect of GFD in patients affected by burning mouth syndrome (BMS), a disease of unknown origin characterized by oral and especially tongue burning sensation, deeply decreasing the quality of life of patients

Enrollment: 40 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

-Primary BMS

Exclusion criteria

• Celiac Disease
• Psychiatric Disorders
• intestinal autoimmune diseases
• Ongoing cancer

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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40 participants in 2 patient groups

Gluten free diet

Experimental group

Description:

BMS patients following a GFD

Treatment:

Dietary Supplement: Gluten Free Diet

Normal Diet

Sham Comparator group

Description:

Patients with BMS maintaing a normal diet

Treatment:

Dietary Supplement: Normal Diet