Effect of Goal-directed Fluid Therapy Using Stroke Volume Variation in Patients Undergoing Free Flap Reconstruction After Head and Neck Cancer Resection

Yonsei University

Status: Completed

Conditions: General Anesthesia

Treatments: Procedure: Conservative fluid therapy; Procedure: Standard fluid therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT02003066

4-2013-0638

Details and patient eligibility

About

Investigators hypothesized that goal-directed fluid therapy using stroke volume variation will improve postoperative recovery in patients undergoing free flap reconstruction after head and neck cancer resection. Investigators will compare the effect of goal-directed fluid therapy using stroke volume variation on recovery in patients undergoing free flap reconstruction after head and neck cancer resection.

Enrollment: 62 patients

Sex: All

Ages: 20 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• adult patients of age over 20 years scheduled for free flap reconstruction after head and neck cancer resection

Exclusion criteria

• valvular heart disease
• congestive heart failure
• liver failure
• renal failure
• pregnant woman
• allergy to hydroxyethyl starch solutions
• coagulation abnormalities

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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62 participants in 2 patient groups

Standard

Experimental group

Treatment:

Procedure: Standard fluid therapy

Conservative

Active Comparator group

Treatment:

Procedure: Conservative fluid therapy